2. Cardiovascular Disease

Cardiovascular Disease

Cardiovascular Disease

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Cardiovascular diseases (CVDs) are the leading causes of death and disability worldwide. CVDs include diseases of the heart, vascular diseases of the brain and diseases of blood vessels. Caused by atherosclerosis, coronary heart disease and cerebrovascular disease are the most common forms of CVDs. Other less common forms of CVDs include rheumatic heart disease and congenital heart disease. A large percentage of CVDs is preventable through the reduction of behavioral risk factors such as tobacco use, physical inactivity and unhealthy diet. Dietary sodium reduction can alleviate the long-term risk of cardiovascular disease events. Statin therapy is an effective intervention in both the primary and secondary preventions of CVDs in those who are at high risk.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-153489D
    FAM labled ISIS 329993 sodium 98%
    FAM labled ISIS 329993 sodiumis a FAM labled ISIS 329993 sodium.
    FAM labled ISIS 329993 sodium
  • HY-153489E
    Cy3 labled ISIS 329993 sodium 98%
    Cy3 labled ISIS 329993 sodium is a Cy3 labled ISIS 329993 sodium.
    Cy3 labled ISIS 329993 sodium
  • HY-153491B
    Olezarsen sodium scrambled negative control 98%
    Olezarsen sodium scrambled negative control is the sequence scrambled negative control of Olezarsen sodium.
    Olezarsen sodium scrambled negative control
  • HY-153491C
    FAM labled Olezarsen sodium 98%
    FAM labled Olezarsen sodiumis a FAM labled Olezarsen sodium.
    FAM labled Olezarsen sodium
  • HY-153491D
    Cy3 labled Olezarsen sodium 98%
    Cy3 labled Olezarsen sodium is a Cy3 labled Olezarsen sodium.
    Cy3 labled Olezarsen sodium
  • HY-153964A
    PF-06478939 TFA 98%
    PF-06478939 TFA is a non-brain-penetrating peptide that is an agonist at oxytocin (OT) receptor and vasopressin receptor with EC50 values of 0.01 nM and 0.078 nM, respectively.
    PF-06478939 TFA
  • HY-153999C
    Rondaptivon pegol sodium scrambled negative control 98%
    Rondaptivon pegol sodium scrambled negative control is the sequence scrambled negative control of Rondaptivon pegol sodium.
    Rondaptivon pegol sodium scrambled negative control
  • HY-153999D
    FAM labled Rondaptivon pegol sodium 98%
    FAM labled Rondaptivon pegol sodiumis a FAM labled Rondaptivon pegol sodium.
    FAM labled Rondaptivon pegol sodium
  • HY-153999E
    Cy3 labled Rondaptivon pegol sodium 98%
    Cy3 labled Rondaptivon pegol sodium is a Cy3 labled Rondaptivon pegol sodium.
    Cy3 labled Rondaptivon pegol sodium
  • HY-15407AS
    Sacubitril-13C4 hemicalcium salt 98%
    Sacubitril-13C4 (hemicalcium salt) is a 13C-labeled and deuterium labeled Sacubitril hemicalcium salt. Sacubitril (AHU-377) hemicalcium salt is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril hemicalcium salt is a component of the heart failure medicine LCZ696.
    Sacubitril-13C4 hemicalcium salt
  • HY-15407BR
    Sacubitril sodium (Standard) 149690-05-1 98%
    Sacubitril (sodium) (Standard) is the analytical standard of Sacubitril (sodium). This product is intended for research and analytical applications. Sacubitril sodium is a potent and orally active NEP (neprilysin) inhibitor, with an IC50 of 5 nM. Sacubitril sodium enhances the tone of the natriuretic peptide (NP) system and exerts significant antihypertensive effects. Sacubitril sodium is a component of the heart failure medicine LCZ696. Sacubitril sodium can be used for the research of heart failure, hypertension and COVID-19.
    Sacubitril sodium (Standard)
  • HY-156209S
    Gb3(d18:1/16:0)-d9 2738376-84-4 98%
    Gb3(d18:1/16:0)-d9 is deuterium labeled Gb3(d18:1/16:0) (HY-156209). Gb3 (d18:1/16:0) (Compound 1) is the Pk antigen of the P blood group system. Gb3 (d18:1/16:0) acts as a cell surface receptor. Gb3 (d18:1/16:0) is used for research on Burkitt's lymphoma, teratocarcinoma, embryonal carcinoma, and Fabry's disease.
    Gb3(d18:1/16:0)-d9
  • HY-156501C
    BT101 sodium scrambled negative control 98%
    BT101 sodium scrambled negative control is the sequence scrambled negative control of BT101 sodium.
    BT101 sodium scrambled negative control
  • HY-156501D
    FAM labled BT101 sodium 98%
    FAM labled BT101 sodiumis a FAM labled BT101 sodium.
    FAM labled BT101 sodium
  • HY-156501E
    Cy3 labled BT101 sodium 98%
    Cy3 labled BT101 sodium is a Cy3 labled BT101 sodium.
    Cy3 labled BT101 sodium
  • HY-15731S1
    Estetrol-d4 (Major) 2734920-42-2 98%
    Estetrol-d4 (Major) is the deuterium labeled Estetrol (HY-15731). Estetrol, an orally active estrogen synthesized exclusively during pregnancy by the human fetal liver, is a selective nuclear estrogen receptor modulator. Estetrol binds ERα as well as ERβ (with a fourfold lower affinity). Estetrol increases eNOS expression/activity and NO synthesis in endothelial cells. Estetrol exerts estrogenic actions on the endometrium or the central nervous system but presents antagonistic effects on the breast. Estetrol can be used in contraception and menopausal hormone research.
    Estetrol-d4 (Major)
  • HY-157639A
    18:2 Lyso PA sodium 98%
    18:2 Lyso PA sodium is an unsaturated lysophosphatidic acid (LysoPA), a lipid mediator mainly present in plasma and thought to be involved in the pathogenesis of acute coronary syndrome (ACS). 18:2 Lyso PA sodium significantly correlates with serum autotaxin (ATX) in peripheral arteries.
    18:2 Lyso PA sodium
  • HY-15834AR
    Eprosartan mesylate (Standard) 144143-96-4
    Eprosartan (mesylate) (Standard) is the analytical standard of Eprosartan (mesylate). This product is intended for research and analytical applications. Eprosartan mesylate (SKF-108566J) is a selective, competitive, nonpeptid and orally active angiotensin II receptor antagonist, used as an antihypertensive. Eprosartan mesylate binds angiotensin II receptor with IC50s of 9.2 nM and 3.9 nM in rat and human adrenal cortical membranes, respectively.
    Eprosartan mesylate (Standard)
  • HY-159698B
    IONIS-DGAT 2Rx sodium scrambled negative control 98%
    IONIS-DGAT 2Rx sodium scrambled negative control is the sequence scrambled negative control of IONIS-DGAT 2Rx sodium.
    IONIS-DGAT 2Rx sodium scrambled negative control
  • HY-159698C
    FAM labled IONIS-DGAT 2Rx sodium 98%
    FAM labled IONIS-DGAT 2Rx sodiumis a FAM labled IONIS-DGAT 2Rx sodium.
    FAM labled IONIS-DGAT 2Rx sodium
Cat. No. Product Name / Synonyms Application Reactivity